Custom In Vivo Toxicology Testing
From our iconic laboratory in the south of England we offer a portfolio of in vivo toxicology assays for global pharmaceutical companies, vaccine researchers and manufacturers, biopharmaceutical startups and their investors, as well as chemical, agrochemical and rodenticide manufacturers.
We are one of the few remaining privately-owned in vivo laboratories in the UK and Europe are trusted by our customers with the essential work of ensuring their products meet regulatory safety requirements.
Integrated Preclinical R&D Packages
In collaboration with Medicilon we offer world-class integrated non-GLP drug candidate development and GLP safety studies across hit identification, synthesis, lead optimisation and candidate selection through to pre-IND safety and efficacy testing.
Our team will help align your business milestones with regulatory requirements.
Standalone Preclinical Studies
When you choose to work with Hoeford you get access to nearly one million square feet of laboratory space and over 3,000 scientists and support personnel in Gosport UK, Boston US, and Shanghai China.
This means we can support your drug discovery and development journey by building regulatory optimisation strategies that do not compromise on quality or scientific rigour, and are efficent and cost-effective.
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Choosing your Proof-of-Concept In Vivo Toxicology Laboratory
In Vivo toxicology proof-of-concept (PoC) testing plays a crucial role in evaluating the potential risks and hazards associated with new compounds in the early stages of lead generation and pre-candidate selection, when developers are assessing the likelihood of scientific success, and investors are calculating the likelihood of financial return on their investment.
Choosing the right toxicology testing provider at this stage is an essential step in ensuring that safety, compliance and risk are clearly defined at what can be a nail-biting time for developers and investors.
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Toxin and Antitoxin Testing
Acute toxicity testing for toxins, alkaloids and immunotoxins
International regulations relating to human health require that all new pharmaceutical drugs are tested for safety prior to use in human volunteers and patients.
A key stage in ensuring the safety of drugs is to conduct toxicity tests in appropriate animal models and acute toxicity studies are just one of a battery of toxicity tests that are used.
These studies are usually conducted in rodents and this test is particularly contentious as it is the only test in pharmaceutical development where lethality is a key endpoint.
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Regulatory Toxicology Results You Can Trust
Compliance
Our fully-compliant toxicology testing programmes are customised to ensure alignment with the appropriate regulatory pathway, delivering results that save time and development costs and get your product to market safely.
Excellence
With each new challenge our scientific and technical experts leverage a 60-year heritage of discipline and commitment to operational excellence, ensuring reliable and predictable outcomes for you and your customers.
Confidence
We act with confidence, determination and a full understanding of your needs and expectations. We communicate with transparency and clarity at every stage of the project to get the results right first time.
Comprehensive
We can conduct one-off testing and multi-year projects that meet the regulatory requirements mandated by MHRA, EHA, FDA and WHO, as well as provide toxicology testing for products manufactured outside the EU that require re-testing at an EU-based facility according to EP, USP or JP guidelines.